Tuesday 9 May 2017

Bioactive compounds from Cyanobacteria and marine fungi

Marine microorganisms are a productive resourse of new pharmacologically dynamic operators and lead structures. Their uncommon living conditions and capacities in the biological community constrains them to create an unfathomable number of bioactive metabolites with new structures. These new mixes may have helpful importance as new medications for people or creatures or for assurance of plants.

The principle point of our work is the examination of developed cyanobacteria and marine parasites for their capability to deliver substances with antibacterial, antifungal, antiviral, cytostatic, immunomodulatory or catalyst inhibitory properties.


Marine microorganisms are a productive resourse of new pharmacologically dynamic operators and lead structures. Their uncommon living conditions and capacities in the biological community constrains them to create an unfathomable number of bioactive metabolites with new structures. These new mixes may have helpful importance as new medications for people or creatures or for assurance of plants.

The principle point of our work is the examination of developed cyanobacteria and marine parasites for their capability to deliver substances with antibacterial, antifungal, antiviral, cytostatic, immunomodulatory or catalyst inhibitory properties.



Cyanobacteria and marine organisms, detached from the Baltic ocean and other sea-going sources, are developed in fermenters as appeared previously. Separates acquired from the biomass and from the way of life media are screened in a few natural test frameworks. From those concentrates, which show intriguing exercises the mindful substances are segregated by a bioactivity-guided seclusion process. Illustration of compound structures, advancement of society conditions and further organic and toxicological tests will take after.

At the division HPLC-DAD, HPLC-MS, NMR and IR are utilized for the basic characterisation of new mixes. A HPLC-NMR-framework (600MHz; including HRMS) will be introduced presently.


Cyanobacteria and marine organisms, detached from the Baltic ocean and other sea-going sources, are developed in fermenters as appeared previously. Separates acquired from the biomass and from the way of life media are screened in a few natural test frameworks. From those concentrates, which show intriguing exercises the mindful substances are segregated by a bioactivity-guided seclusion process. Illustration of compound structures, advancement of society conditions and further organic and toxicological tests will take after.

At the division HPLC-DAD, HPLC-MS, NMR and IR are utilized for the basic characterisation of new mixes. A HPLC-NMR-framework (600MHz; including HRMS) will be introduced presently.